General Scientific Session I: Surgery at the Anatomical Edge
Chapter 1
The Geometry Of Education: Patterns For Growth
Vincent C. Traynelis, M.D.
Chapter 2
Surgical Approaches to the Craniocervical Junction for the Resection of Chordomas
Raj K. Shrivastava, M.D., Chandranath Sen, M.D., and Peter Costantino, M.D.
Chapter 3
Exploring the Limits of Survivability: Rational Indications for Decompressive Craniectomy and Resection of Cerebral Contusions in Adults
Austin R. T. Colohan, M.D., Samer Ghostine, M.D., and Domenic Esposito, M.D.
Chapter 4
Application of Endoscopy to Third Ventricular Tumors
Chapter 5
Glial Reactivity After Damage: Implications for Scar Formation and Neuronal Recovery
Cecily E. Hamill, Anna Goldshmidt, Olivier Nicole, Robert J. Mckeon, Daniel J. Brat, and Stephen F. Traynelis
Chapter 6
CNS Internet Tools and Neurosurgery
Joel D. MacDonald, M.D.
Chapter 7
Craniocervical Developmental Anatomy and Its Implications
Arnold H. Menezes, M.D.
Chapter 8
New Developments in the Surgical Management of Spinal Cord Compression Caused by Metastatic Tumor
Roy A. Patchell, M.D.
Chapter 9
Intracranial atherosclerotic disease: Common, dangerous, and treatable
Ricardo A. Hanel, M.D., Elad I. Levy, M.D., Lee R. Guterman, Ph.D., M.D., L. Nelson Hopkins, M.D.
Chapter 10
Intramedullary Spinal Cord Tumors: Molecular insights and Surgical Innovation
Andrew T. Parsa, M.D., Ph.D., John H. Chi, M.D., M.P.H., Frank L. Acosta, Jr., M.D., Christopher P. Ames, M.D., and Paul C. McCormick, M.D., M.P.H.
General Scientific Session II: Bridging the Gap: Bench to Bedside, Conception to Implementation
Chapter 11
Accuray, Incorporated: A Neurosurgical Business Case Study
John R. Adler, Jr., M.D.
Chapter 12
Human Embryonic Stem Cells: Hype or Hope?
Viviane S. Tabar, M.D.
Chapter 13
Modeling and Preclinical Trials for Gliomas
Chapter 14
Pituitary Adenomas and Craniopharyngiomas
Enrico de Divitiis, M.D., Felice Esposito, M.D., Luigi M. Cavallo, M.D., Ph.D., and Paolo Cappabianca, M.D.
Chapter 15
Hydrocephalus: New Theories and New Shunts?
Marvin Bergsneider, M.D.
Chapter 16
Neurostimulation for Epilepsy, Including a Pilot Study of Anterior Nucleus Stimulation
Nina M. Graves, Pharm.D. and Robert S. Fisher M.D., Ph.D.
Chapter 17
Intrinsic Optical Signal Imaging of Normal and Abnormal Physiology in Animals and Humans—Seeing the Invisible
Minah Suh, Ph.D., Saadat Shariff, B.A., Sonya Bahar, Ph.D., Ashesh D. Mehta, M.D., Ph.D., and Theodore H. Schwartz, M.D.
Chapter 18
Selective Ablation of Nociceptive Neurons for Elimination of Hyperalgesia and Neurogenic Inflammation
Gabriel C. Tender, M.D., Stuart Walbridge, B.S., Zoltan Olah, Ph.D., Laszlo Karai, M.D., Michael Iadarola, Ph.D., Edward H. Oldfield, M.D., and Russell R. Lonser, M.
Chapter 19
Conception to Implication: Craniocervical Junction Database and Treatment Algorithm
Arnold H. Menezes, M.D.
Chapter 20
Advances in Biomaterials that Led to the Artificial Disc
Jeremy C. Wang, M.D. and Regis W. Haid, Jr., M.D.
General Scientific Session III: Surgery at the Crossroads
Chapter 21
Fractures of the Upper Thoracic Spine:Approaches and Surgical Management
Sean D Christie, M.D., John Song, M.D., and Richard G Fessler, M.D., Ph.D.
Chapter 22
Neurosurgery at the Crossroads: Integrated Multidisciplinary Management of 449 Patients with Brain Arteriovenous Malformations
Rose Du, M.D., Ph.D., Michael W. McDermott, M.D., Christopher F. Dowd, M.D., William L. Young, M.D., and Michael T. Lawton, M.D.
Chapter 23
Treatment of Spinal Vascular Malformations:
L. Fernando Gonzalez, M.D. and Robert F. Spetzler, MD
Chapter 24
Surgery for Parkinson’s Disease: Integration of Neurology and Neurosurgery
Philip A. Starr M.D., Ph.D.
Chapter 25
Biomechanical Considerations for Stabilization of the Craniovertebral Junction
Curtis A. Dickman, M.D., and Gregory P. Lekovic, M.D., Ph.D., J.D.
Chapter 26
Neurosurgery In Africa
ABDESLAM EL KHAMLICHI, M.D.
Chapter 27
Surgery at the Crossroads: Craniocervical Neoplasms
Arnold H. Menezes, M.D., Vincent C. Traynelis, M.D., Albert J. Fenoy, M.D., Bruce J. Gantz, M.D., Stephen F. Kralik, M.D., and Kathleen A. Donovan, A.R.N.P.
Chapter 28
Emerging Indications in Stereotactic Radiosurgery: The First Application of Cellular Surgery
Douglas Kondziolka, M.D., M.Sc., F.R.C.S.C., L. Dade Lunsford, M.D., John C. Flickinger, M.D., and Ajay Niranjan, M.Ch.
Chapter 29
Multimodality Treatment of Pituitary Adenomas
Nelson M. Oyesiku, M.D., Ph.D.
Chapter 30
When it is Not Cervical Radiculopathy: Thoracic Outlet Syndrome—A Prospective Study on Diagnosis and Treatment
J. Paul Muizelaar, M.D., Ph.D., and Marike Zwienenberg-Lee, M.D.
Chapter 31
Graft Substitutes for Use in Spinal Fusions
Gregory A. Helm, M.D., Ph.D.
General Scientific Session IV: A Lifetime of Experience, A Future of Possibilities
Chapter 32
Contemporary Management of Anterior Circulation Aneurysms
Michiyasu Suzuki, M.D.
Chapter 33
Spinal Dysraphism: Impact of Technique and Technology on Expectations
David G. McLone, M.D., Ph.D.
Chapter 34
Functional Neurosurgery: Past, Present, and Future
A. L. Benabid, M.D., Ph.D., S. Chabardes, M.D., E. Seigneuret, M.D., P. Pollak, M.D., V. Fraix, M.D., P. Krack, M.D., J. F. LeBas, M.D., Ph.D., S. Grand, M.D., and B. Piallat, Ph.D.
Chapter 35
Decompression, Arthrodesis, and Arthroplasty: Decision Making in the Surgical Treatment of Lumbar Disc Disease
Brian E. Snell, M.D. and Dennis J. Maiman, M.D., Ph.D.
Chapter 36
Treatment of Hydrocephalus: Mere Survival is Not Enough
Marion L. Walker, M.D.
Chapter 37
One Size Does Not Fit All: Choosing a Treatment Strategy for Trigeminal Neuralgia
Giovanni Broggi, M.D., Paolo Ferroli, M.D., Angelo Franzini, M.D., and Luciano Galosi, M.D.
Chapter 38
Evolution of Management Strategies for Cerebral Gliomas: The Effects of Science and Technology
Mitchel S. Berger, M.D., and G. Evren Keles, M.D.
Chapter 39
Lifetime Experiences and Where We are Going: Chiari I with Syringohydromyelia—Controversies and Development of Decision Trees
Arnold H. Menezes, M.D., Jeremy D.W. Greenlee, M.D., and Kathleen A. Donovan, A.R.N.P.
Chapter 40
The Management of Traumatic Brain Injury: The Development of Guidelines and Their Influence
Raymond F. Sekula, M.D. and Jack E. Wilberger, M.D., F.A.C.S.
Chapter 41
Innovative Internal Fixation for Cervical Spine Fractures
Eric M. Horn, M.D., Ph.D., Peter H. Maughan, M.D., L. Fernando Gonzalez, M.D., and Stephen M. Papadopoulos, M.D.
Chapter 42
Not Your Father’s Lobotomy: Psychiatric Surgery Revisited
Brian Harris Kopell, M.D., Andre G Machado, M.D. Ph.D., Ali R. Rezai M.D
Chapter 43
Surgical Management of Cervical Disc Disease: From No Fusion to Fusion and Back Again
Iman Feiz-Erfan, M.D., Jeffrey D. Klopfenstein, M.D., Nicholas C. Bambakidis, M.D., and Volker K. H. Sonntag, M.D.
Chapter 44
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) Prevents Apoptosis and Improves Functional Outcome in Experimental Spinal Cord Contusion Injury
Yoon Ha, M.D., Ph.D., Hyune Seon Park, M.D., Chong Woon Park, M.D., Seung Hwan Yoon, M.D., Ph.D., So Ra Park, M.D., Ph.D., Dong Keun Hyun, M.D., Ph.D., Eun Young Kim, M.D., Ph.D., and Hyung Chun Park M.D., Ph.D.
Resident And Young Investigator Awards
Chapter 45
Synthes Award for Resident Research on Brain and Craniofacial Injury: Normoxic Ventilatory Resuscitation After Controlled Cortical Impact Reduces Peroxynitrite-Mediated Protein Nitration in the Hippocampus
Edward S. Ahn, M.D., Courtney L. Robertson, M.D., Viktoria Vereczki, M.D., Gloria E. Hoffman, Ph.D., and Gary Fiskum, Ph.D.
Chapter 46
Healthcare Management 101
Jonathan A. Tuttle, M.D., William Hamilton, M.B.A., M.H.A., and Cargill H. Alleyne, Jr., M.D.
Chapter 47
Acoustic Neuroma Surgical Cost and Outcome by Hospital Volume
Marc S. Schwartz, M.D., William H. Slattery, M.D., Mark Oppenheimer, M.S., and Laurel M. Fisher, Ph.D.
Chapter 48
Nociceptive On- and Off-Cells in the Mesopontine Tegmentum
Jonathan Dennis Carlson, M.D.., Ph..D., Nathan Richard Selden, M.D., Ph.D., Kim James Burchiel, M.D., and Mary Magdalen Heinricher, Ph.D.
Chapter 49
Simvastatin Attenuates Experimental Cerebral Vasospasm and Ameliorates Serum Markers of Neuronal and Endothelial Injury in Patients After Subarachnoid Hemorrhage: A Dose-Response Effect Dependent on Endothelial Nitric Oxide Synthase
Matthew J. McGirt, M.D., Graeme F. Woodworth, B.S., Gustavo Pradilla, M.D., Federico Legnani, M.D., David Warner, M.D., Rafael Tamargo, M.D., Richard Clatterbuck, M.D., John R. Lynch, M.D., and Daniel T. Laskowitz, M.D.
Chapter 50
Deep Brain Stimulation for Generalized Dystonia and Spasmodic Torticollis: An Examination of the Rate and Extent of Improvement
Richard G. Bittar, M.B.B.S., Ph.D., John Yianni, M.R.C.S., ShouYan Wang, Ph.D., Xuguang Liu, M.D., Ph.D., Dipankar Nandi, M.B.B.S., M.Chir., D.Phil., Carole Joint, R.G.N., Richard Scott, Ph.D., Peter G. Bain, M.D., Ralph Gregory, M.D., John Stein, D.Phil.
Chapter 51
Bone Marrow-Derived Flk-1–Expressing CD34+ Cells Contribute To the Endothelium of Tumor Vessels in Mouse Brain
J. G. Santarelli, V. Udani, C. Y. Yung, S. Cheshier, A. Wagers, R. A. Brekken, I. Weissman, and V. Tse
Chapter 52
Extent of Glioma Resection Using Low-field (0.2 T) versus High-field (1.5 T) Intraoperative MRI and Image-guided Frameless Neuronavigation
Marvin Bergsneider, M.D., Nouzhan Sehati, M.D., Pablo Villablanca, M.D., David L. McArthur, Ph.D., Donald P. Becker, M.D., and Linda M. Liau, M.D., Ph.D.